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Nuvectis Pharma Rises in Pre-Market Following FDA Orphan Drug Designation for NXP800, Fueling Optimism Ahead of Key Clinical Data

Global Markets News

Nuvectis Pharma (NASDAQ: NVCT) has achieved a significant milestone with the U.S. Food and Drug Administration (FDA) granting Orphan Drug Designation for its lead candidate, NXP800. This designation, specifically for the treatment of ARID1a-deficient ovarian, fallopian tube, and primary peritoneal cancers, marks a critical step forward in Nuvectis’s mission to address unmet needs in oncology. Orphan Drug Designation: A Strategic Advantage The FDA’s Orphan Drug Designation is awarded to drugs that show promise in treating rare diseases affecting fewer than 200,000 people in the U.S. For Nuvectis, this designation not only validates the potential of NXP800 but also provides several strategic benefits. These include tax credits for clinical trial costs, exemption from certain FDA fees, and potentially seven years of market exclusivity upon approval. NXP800 targets ARID1a-deficient cancers, a subset of ovarian cancers that present significant treatment challenges. The Orphan Drug Designation underscores the importance of this candidate in potentially offering a new, more effective treatment option for patients with this specific genetic mutation. Background and Market Impact This latest achievement builds on Nuvectis Pharma’s earlier successes. Earlier this year, the FDA granted Fast Track Designation to NXP800 for its development in platinum-resistant, ARID1a-mutated ovarian cancer. The Fast Track status, combined with the Orphan Drug Designation, highlights the urgent need for innovative treatments in this space and positions NXP800 as a potential game-changer in oncology. Financial analysts have taken note of Nuvectis’s progress. H.C. Wainwright recently reiterated its buy rating for Nuvectis, setting a price target of $21. This optimistic outlook reflects the market’s confidence in the company’s strategic direction, particularly as it prepares to release key clinical data later this year. Anticipation for Upcoming Results The next few months are expected to be pivotal for Nuvectis Pharma. The company is poised to share updates from its ongoing Phase 1b clinical trial of NXP800, which targets patients with platinum-resistant, ARID1a-mutated ovarian cancer. This trial is being closely watched, as positive results could significantly advance the development of NXP800, bringing it closer to pivotal trials and eventual regulatory approval. Additionally, Nuvectis is also conducting a Phase 1a dose escalation study for NXP900, its second key candidate, which targets YES1/SRC-driven tumors. Updates from this study are expected to provide further insights into the safety and potential efficacy of NXP900. ### Nuvvectis' Full announcment, titled " Nuvectis Pharma Announces Orphan Drug Designation Granted by the FDA for NXP800 for the Treatment of ARID1a-deficient Ovarian, Fallopian Tube, and Primary Peritoneal Cancers" was published on August 29th, 2024. ### This article is for informational purposes only and is not intended to serve as financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the article is subject to. https://justpaste.it/fcm9n/pdf. Global Markets News Network is a commercial digital brand compensated to provide coverage of innovative companies and industries and it is thus subject to conflicts of interest. Contact Details Global Markets News News Coverage ronald@futuremarketsresearch.com

August 29, 2024 08:20 AM Eastern Daylight Time

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Navigate your Investment Roadmap with Select Sector SPDR ETFs

Select Sector SPDR

In an era where market dynamics shift as swiftly as the winds, Select Sector SPDR ETFs remain a beacon for investors aiming to harness the potential of sector-specific investments. Tailored to meet the diverse needs of both individual and institutional investors, these ETFs chart a course for strategic portfolio management by distilling the vast S&P 500 into accessible segments. Focused Investment Across Diverse Sectors Select Sector SPDR ETFs stand out by offering a focused approach to investing, breaking down the broad landscape of the S&P 500 into key sectors. This segmentation allows investors to pinpoint their investments according to specific economic areas, aligning their portfolios with their investment goals, risk assessments, and market perspectives. Below is a glimpse into the diverse holdings that form the core of the Select Sector SPDR ETFs: Communication Services Select Sector SPDR Fund (XLC): Zooms in on the telecommunications and media sectors, capturing the pulse of digital communication. Consumer Discretionary Select Sector SPDR Fund (XLY): Targets the vibrant consumer goods and services sector, from retail giants to entertainment behemoths. Consumer Staples Select Sector SPDR Fund (XLP): Focuses on essential consumer goods and services, providing stability in fluctuating markets. Energy Select Sector SPDR Fund (XLE): Powers through with a dedicated look at the energy sector, from fossil fuels to renewable resources. Financials Select Sector SPDR Fund (XLF): Encompasses the robust banking, investment, and insurance industries, the backbone of economic infrastructure. Health Care Select Sector SPDR Fund (XLV): Centers on the pharmaceuticals, healthcare equipment, and services sectors, addressing global health needs. Industrials Select Sector SPDR Fund (XLI): Broadens the horizon with manufacturing, construction, and logistics firms. Materials Select Sector SPDR Fund (XLB): Covers the foundational chemicals, construction materials, and packaging industries. Real Estate Select Sector SPDR Fund (XLRE): Opens doors to commercial real estate services and REITs. Technology Select Sector SPDR Fund (XLK): Accelerates into the information technology and electronics sectors, powering innovation and connectivity. Utilities Select Sector SPDR Fund (XLU): Illuminates the path with utility companies, ensuring the flow of essential services. A Path for Strategic Investment By offering a lens through which to invest in specific sectors, Select Sector SPDR ETFs enable investors to steer their portfolios with confidence and clarity. The ETFs’ commitment to transparency and strategic focus empowers investors to adapt and thrive amidst the ebb and flow of market conditions. In the evolving landscape of the financial markets, Select Sector SPDR ETFs stand as a testament to the power of targeted investment. Through detailed sector analysis and dedicated portfolio exposure, these ETFs offer a distinguished pathway for those seeking to refine their investment strategies with sector-specific allocations. About Select Sector SPDR ETFs Select Sector SPDR ETFs are a series of exchange-traded funds designed to provide investors with an effective way to engage in sector-specific investment strategies. By segmenting the S&P 500 into distinct sectors, Select Sector SPDR ETFs furnish investors with the tools necessary for targeted and strategic investment decisions. DISCLAIMER: This is a work of research and should not be taken as investment or financial advice. Therefore, Select Sector SPDRs or the publisher is not liable for any decision made based on the publication. About the Company: Select Sector SPDR ETFs offer flexibility and customization opportunities. Many investors have similar outlooks, but no two are exactly alike. Select Sector SPDR ETFs let investors select the sectors that best meet their investment goals. DISCLOSURES The S&P 500 Index is an unmanaged index of 500 common stocks that is generally considered representative of the U.S. stock market. The index is heavily weighted toward stocks with large market capitalizations and represents approximately two-thirds of the total market value of all domestic common stocks. The S&P 500 Index figures do not reflect any fees, expenses or taxes. An investor should consider investment objectives, risks, fees and expenses before investing. One may not invest directly in an index. Transparent ETFs provide daily disclosure of portfolio holdings and weightings All ETFs are subject to risk, including loss of principal. Sector ETF products are also subject to sector risk and nondiversification risk, which generally will result in greater price fluctuations than the overall market. Diversification does not eliminate risk. An investor should consider investment objectives, risks, charges and expenses carefully before investing. To obtain a prospectus, which contains this and other information, call 1-866-SECTOR-ETF (732-8673) or visit www.sectorspdrs.com. Read the prospectus carefully before investing. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is distributor for the Select Sector SPDR Trust. Media Contact: Company: Select Sector SPDRs Contact: Dan Dolan* Address: 1290 Broadway, Suite 1000, Denver, CO 80203 Country: United States Email: dan.dolan@sectorspdrs.com Website: https://www.sectorspdrs.com/ *Dan Dolan is a Registered Representative of ALPS Portfolio Solutions Distributor, Inc. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is the distributor for the Select Sector SPDR Trust. SEL007734 EXP 10/31/24 Contact Details Dan Dolan +1 203-935-8103 dan.dolan@sectorspdrs.com Company Website https://www.sectorspdrs.com/

August 22, 2024 05:00 AM Eastern Daylight Time

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NAVEX to Demystify IT Risk Communication at ISACA GRC Conference

NAVEX Global

NAVEX, the global leader in integrated risk and compliance management software, will deliver a key session at the upcoming ISACA Governance, Risk, and Control (GRC) Conference in Austin, Texas, August 12-14, 2024. The session, " Getting Our Wires Crossed: How to Speak IT Risk as a Compliance Professional," will be presented by Kyle Martin, Vice President of GRC Solutions at NAVEX, and Robert Clark, Chief Audit and Compliance Officer at Howard University. In an era where cybersecurity threats and regulatory pressures are at an all-time high, the ability to effectively communicate IT risks across organizational silos has become a critical skill for compliance professionals. Attendees can join the session, CS 7–4, on August 13th at 11:00 to gain valuable insights into: Understanding and translating risk and compliance terminology. Evaluating program maturity levels and their organizational implications. Assessing risks and controls across all business facets, including third-party risk management. Crafting compelling IT risk reports for executive teams and board directors. "In today's interconnected business environment, the ability to translate IT risk insights into compelling narratives for CEOs is no longer optional—it's essential," said Kyle Martin. "As a result, this session aims to empower compliance professionals with the tools they need to navigate this critical intersection confidently." The ISACA GRC Conference, now in its 11th year, brings together leading minds in governance, risk management, and control to provide world-class content and practical guidance. NAVEX's participation underscores its commitment to advancing the field of integrated risk and compliance management. For more information about NAVEX's participation in the ISACA GRC Conference 2024 or to schedule an interview with the speakers, please contact Senior Public Relations Manager, Scott Levesque at scott.levesque@navex.com. NAVEX is trusted by thousands of customers worldwide to help them achieve the business outcomes that matter most. As the global leader in integrated risk and compliance management software and services, we deliver solutions through the NAVEX One platform, the industry’s most comprehensive governance, risk and compliance (GRC) information system. For more information, visit NAVEX.com and our blog. Follow us on Twitter and LinkedIn. Contact Details Navex Global scott.levesque@navex.com Company Website https://navex.com

August 06, 2024 08:00 AM Eastern Daylight Time

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Ocean Power Technologies CEO Philipp Stratmann Announces Contract for AI-Enhanced PowerBuoy

Ocean Power Technologies Inc

Ocean Power Technologies (OPT), a leader in innovative ocean energy solutions, has secured a significant new contract for the immediate delivery of a PowerBuoy equipped with Merrows, its cutting-edge Artificial Intelligence capable Maritime Domain Awareness Solution. CEO Philipp Stratmann shared this exciting news with Steve Darling from Proactive, highlighting that this contract, focused on deployment in the Middle East, is set to generate revenues within the current quarter. In his discussion with Steve Darling from Proactive, Stratmann emphasized that this achievement builds on the company’s previous announcement of its selection as a preferred supplier for its Merrows-equipped buoys in the region. This new revenue-generating contract underscores OPT’s continued business growth across all its product lines, including WAM-Vs (Wave Adaptive Modular Vessels) and PowerBuoys. Stratmann elaborated on the strategic importance of this shipment, which features a solar and wind-powered system. He noted that it demonstrates OPT’s capability to provide robust and versatile solutions capable of servicing a wide range of marine environments globally. The deployment of this AI-enhanced PowerBuoy not only strengthens OPT's presence in the Middle East but also exemplifies its commitment to delivering advanced maritime technology solutions worldwide. Contact Details Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

July 17, 2024 10:37 AM Eastern Daylight Time

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DB Schenker Showcases Thought Leadership in Import/Export Logistics Through New Video Series on the Port of Halifax

DB Schenker

DB Schenker, a global leader in logistics and supply chain management, is thrilled to announce the launch of an exclusive video series focused on the Port of Halifax. This series, designed for logistics experts and import/export professionals, highlights the Port of Halifax's strategic importance and innovative practices in global trade. The video series features insightful interviews with prominent figures, including: Marilisa Benigno, Honorary Consul of Italy, Atlantic Region Suzanne Rix, Honorary Consul of Germany for the Maritime Provinces Captain Allan Gray, President, and CEO of the Halifax Port Authority Jonathan Chia, Head of Commercial at PSA Halifax David Thomas, Executive Director at The PIER Key Highlights: Vision and Mission of the Port of Halifax: Capt. Gray elaborates on the Port of Halifax's mission to be Canada’s preferred gateway, emphasizing its global connectivity and economic impact. “Every day, we connect with markets in Central Canada, the U.S. Midwest and countries around the world,” said Capt. Gray. “These connections foster opportunities for business and support thousands of jobs today. Looking ahead, the port will continue to integrate innovation, sustainability and community into how we do business.” Economic Impact: The Port of Halifax is a significant economic driver. A recent study showed the port generates billions of dollars in economic activity annually, contributing $1.6 billion in labour income and supporting over 25,000 jobs in the region. Jonathan Chia discusses the port’s role in reducing logistics costs for inland Canada and its strategic positioning as a gateway port. Global Connectivity and Innovation: The port’s connection to more than 150 countries worldwide, along with substantial investments in mega cranes and digitalization, positions Halifax as a key player on the global stage. Sustainability and Community Engagement: The series delves into the port's collaborative efforts with the Port of Hamburg to accelerate decarbonization and sustainability initiatives. Capt. Gray will also highlight the port's commitment to community integration and sustainable growth through innovative projects and partnerships. Future Infrastructure Developments: Viewers will gain insights into the port's 50-year plan, which includes expanding rail capacity and optimizing existing infrastructure to meet future demand while focusing on sustainable growth. Strengthening Italy-Canada Relations: Marilisa Benigno, Honorary Consul of Italy, Atlantic Region shares the consulate’s efforts to strengthen ties between Italy and Canada through various initiatives, including visa facilitation, cultural events, and business collaborations. German-Canadian Collaboration: Suzanne Rix, Honorary Consul of Germany for the Maritime Provinces, discusses the burgeoning relationship between Germany and Halifax, particularly in the fields of hydrogen and wind energy. The collaboration between the Port of Hamburg and the Port of Halifax in seeking to decarbonize their respective route is a significant step towards sustainable trade practices. Innovation and the Living Lab: David Thomas, Executive Director at The PIER, explains the role of The PIER as Canada’s first living lab to help solve supply chain and logistics challenges. The PIER’s projects emphasize efficiency, resilience, transparency, and sustainability in supply chains​. Catch the full Interviews on DB Schenker’s LinkedIn: The complete series of interviews is available on DB Schenker’s LinkedIn page, offering valuable insights for professionals in the logistics and supply chain sectors. Follow the link to stay updated and engage with industry leaders: DB Schenker LinkedIn. About DB Schenker With around 76,600 employees at more than 1,850 locations in over 130 countries, DB Schenker is one of the world’s leading logistics service providers. The company operates land, air, and ocean transportation services, and it also offers comprehensive logistics and global supply chain management solutions from a single source. Aiming for a sustainable future of the logistics industry, DB Schenker continuously invests in innovative transport solutions, renewable energies, and low-emission products for its customers. Contact Details Nicholas Leighton +1 949-478-5880 nick.leighton@nettresultsLLC.com Company Website https://www.dbschenker.com/usa

July 16, 2024 11:55 AM Eastern Daylight Time

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Ocean Power Technologies Selected as Preferred Supplier for PowerBuoy with Merrows in Middle East

Ocean Power Technologies Inc

Ocean Power Technologies CEO Philipp Stratmann joined Steve Darling from Proactive to announce that the company has been selected as a preferred supplier for a PowerBuoy equipped with Merrows, its Artificial Intelligence-capable Maritime Domain Awareness Solution. This selection is for an immediate delivery opportunity in the Middle East. The contract, once finalized, is expected to generate revenues in the current quarter. The company had previously announced the completion of engineering for Merrows to operate in hot climates. Stratmann highlighted that this development is another example of the company's growth in its PowerBuoy business. He emphasized that the Middle East presents significant opportunities for Merrows and the potential to integrate additional Wave Adaptive Modular Vessels (WAM-Vs) into their operations. This strategic move underscores Ocean Power Technologies' commitment to expanding its market presence and leveraging its advanced maritime technologies to meet the growing demand in the Middle East. Contact Details Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

June 26, 2024 10:27 AM Eastern Daylight Time

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Select Sector SPDR ETFs: A Focused Approach for Sector-Specific Portfolio Management

Select Sector SPDR

In the ever-changing landscape of the financial markets, Select Sector SPDR ETFs present a method for investors looking to engage in sector-specific investments. By breaking down the S&P 500 into distinct sectors, these ETFs provide a pathway for both individual and institutional investors to craft more targeted and strategic investment portfolios. The Select Sector SPDR ETFs encompass a range of sectors, each represented by a dedicated ETF. This structure allows investors to focus their investments on specific areas of the economy, depending on their investment objectives, risk tolerance, and market outlook. Overview of Select Sector SPDR ETFs: Communication Services Select Sector SPDR Fund (XLC): Focuses on telecommunications and media companies. Consumer Discretionary Select Sector SPDR Fund (XLY): Targets companies focused on non-essential goods and services such as luxury items, travel, and leisure. Consumer Staples Select Sector SPDR Fund (XLP): Concentrates on essential consumer goods and services like food, clothing, and personal products. Energy Select Sector SPDR Fund (XLE): Dedicated to the energy sector, focused on oil and natural gas. Financials Select Sector SPDR Fund (XLF): Encompasses banking, investment, and insurance industries. Health Care Select Sector SPDR Fund (XLV): Focuses on pharmaceuticals, healthcare equipment, and services. Industrials Select Sector SPDR Fund (XLI): Includes manufacturing, construction, and logistics firms. Materials Select Sector SPDR Fund (XLB): Covers the chemicals, construction materials, and packaging industries. Real Estate Select Sector SPDR Fund (XLRE): Targets commercial real estate services and REITs. Technology Select Sector SPDR Fund (XLK): Concentrates on the information technology, semiconductor, and electronics sectors. Utilities Select Sector SPDR Fund (XLU): Dedicated to electric and gas utility companies. By offering a straightforward and transparent approach to investing in specific sectors, Select Sector SPDR ETFs enable investors to adapt their investment strategies in response to changing market conditions. The Select Sector SPDR ETFs offer a focused approach to investment, allowing for detailed sector analysis and strategic portfolio management. As the financial landscape continues to evolve, these ETFs provide a valuable tool for investors looking to refine their investment strategies through sector-specific allocations. DISCLAIMER: This is a work of research and should not be taken as investment or financial advice. Therefore, Select Sector SPDRs or the publisher is not liable for any decision made based on the publication. About the Company: Select Sector SPDR ETFs offer flexibility and customization opportunities. Many investors have similar outlooks, but no two are exactly alike. Select Sector SPDR ETFs let investors select the sectors that best meet their investment goals. DISCLOSURES The S&P 500 Index is an unmanaged index of 500 common stocks that is generally considered representative of the U.S. stock market. The index is heavily weighted toward stocks with large market capitalizations and represents approximately two-thirds of the total market value of all domestic common stocks. The S&P 500 Index figures do not reflect any fees, expenses or taxes. An investor should consider investment objectives, risks, fees and expenses before investing. One may not invest directly in an index. Transparent ETFs provide daily disclosure of portfolio holdings and weightings All ETFs are subject to risk, including loss of principal. Sector ETF products are also subject to sector risk and nondiversification risk, which generally will result in greater price fluctuations than the overall market. Diversification does not eliminate risk. An investor should consider investment objectives, risks, charges and expenses carefully before investing. To obtain a prospectus, which contains this and other information, call 1-866-SECTOR-ETF (732-8673) or visit www.sectorspdrs.com. Read the prospectus carefully before investing. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is distributor for the Select Sector SPDR Trust. Media Contact: Company: Select Sector SPDRs Contact: Dan Dolan* Address: 1290 Broadway, Suite 1000, Denver, CO 80203 Country: United States Email: dan.dolan@sectorspdrs.com Website: https://www.sectorspdrs.com/ *Dan Dolan is a Registered Representative of ALPS Portfolio Solutions Distributor, Inc. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is the distributor for the Select Sector SPDR Trust. SEL007597 EXP 8/31/24 Contact Details Dan Dolan +1 203-935-8103 dan.dolan@sectorspdrs.com Company Website https://www.sectorspdrs.com/

June 24, 2024 05:00 AM Eastern Daylight Time

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Pyxis Tankers chairman and CEO on market outlook and growth strategies

Pyxis Tankers Inc

Pyxis Tankers Inc (NASDAQ:PXS) chairman and CEO Valentios (Eddie) Valentis, talked with Proactive about the recent Posidonia shipping event and its impact on the shipping industry. Valentis shared his insights on the optimistic outlook for shipping sectors despite global headwinds. He highlighted that industry players are leveraging substantial cash balances to pay down debt, renew fleets, and make significant shareholder distributions. Valentis noted the strong chartering environment for product tankers, influenced by tighter inventories and changing trade patterns due to geopolitical conflicts. Discussing market conditions, Valentis provided an update on product tankers and dry bulk sectors. He mentioned the positive near-term outlook supported by refinery additions and OPEC+ supply cuts. Additionally, Valentis shared Pyxis Tankers' recent performance, including Q1 2024 financial results, fleet expansion, and new acquisitions. He also outlined the company's shareholder value enhancement initiatives, such as share buyback programs and reducing convertible preferred shares. Valentis said the favourable prospects for both sectors and its existing capital resources allow Pyxis to actively pursue value-enhancing investment opportunities. Contact Details Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com

June 11, 2024 11:40 AM Eastern Daylight Time

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NOVUS INK Advisors and Solidus Capital Group Team-up to Serve Growing Transatlantic Commercial Interests of Mid-Market Enterprises

NOVUS INK Advisors

NOVUS INK Advisors and Solidus Capital Group signed a services agreement today to provide integrated senior advisory and execution services to small-and mid-market enterprises amid thriving commercial interests between the United States and Europe. The two firms aim to accelerate client services by combining expertise and resources to support growth into new markets, encompassing management counsel, valuation, performance tracking, board advisory, marketing, communication, public and government affairs. The collaboration will enable NOVUS INK Advisors and Solidus Capital Group to meet the unique needs of global small-and mid-market enterprise clients operating across business-to-consumer, business-to-business, and business-to-government segments. The transatlantic economy is proving remarkably robust in the face of global economic and geopolitical disruptions. No two other regions in the world are as deeply integrated as the United States and Europe, according to the 2024 Transatlantic Economy Report from the U.S. Chamber of Commerce, AmCham EU, Johns Hopkins SAIS and the Transatlantic Leadership Network. The report states: "the $8.7 trillion transatlantic economy employs more than 16 million workers in mutually onshored jobs on both sides of the Atlantic. It is the largest and wealthiest market in the world, accounting for half of total global personal consumption and close to one-third of world GDP in purchasing power. Ties are solid in foreign direct investment, portfolio investment, banking claims, trade and affiliate sales in goods and services, digital links, energy, mutual R&D investment, patent cooperation, technology flows, and sales of knowledge-intensive services." The services agreement will be overseen by a committee chaired by Pia De Lima and Daniel Diaz, NOVUS INK Advisors' Managing Partners, and Andreas Dal Santo, Solidus Capital Group's Managing Director. NOVUS INK Advisors is based in Miami. Solidus Capital Group, affiliated with Atlantic Business Labs, is based in New York. NOVUS INK Advisors is a communication, public and government affairs lobbying firm. NOVUS INK Advisors' practice areas include Corporate, Band and Product Reputation, Business Strategy, Crisis and Reputation Risk, Financial Services, Investor Relations, Mergers & Acquisitions, Brand and Product Marketing Communications Strategy, and Public and Government Affairs. NOVUS INK Advisors is a registered lobbying firm. To learn more, visit: www.NovusInk.com. Solidus Capital Group specializes in management consulting, business valuation, and board advisory services for firms expanding into North America, Latin America, and Europe. It is spearheading an ecosystem of companies, consultants, and subject matter experts with experience from different industries and regions to support corporate and institutional clients' global strategies and growth into new markets. To learn more, visit www.solidus-capital.com. CONTACTS: NOVUS INK Advisors: client.services@NovusInk.com Solidus Capital Group: client.services@Solidus-Capital.com Contact Details NOVUS INK Advisors Client Services client.services@NovusInk.com Company Website https://www.novusink.com/about

June 11, 2024 09:30 AM Eastern Daylight Time

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